ADPD 2025 Bibliography

Ehrenberg, A. J., et al. (2025). "Pathways underlying selective neuronal vulnerability in Alzheimer's disease: Contrasting the vulnerable locus coeruleus to the resilient substantia nigra." Alzheimers Dement 21(3): e70087.

CHOLESTEROL HOMEOSTASIS MECHANISMS UNDERLIE SELECTIVE VULNERABILITY TO ALZHEIMER’S DISEASE IN AMINERGIC BRAINSTEM NUCLEI

Ehrenberg, A. J., et al. (2017). "Quantifying the accretion of hyperphosphorylated tau in the locus coeruleus and dorsal raphe nucleus: the pathological building blocks of early Alzheimer's disease." Neuropathol Appl Neurobiol 43(5): 393-408.

Theofilas, P., et al. (2017). "Locus coeruleus volume and cell population changes during Alzheimer's disease progression: A stereological study in human postmortem brains with potential implication for early-stage biomarker discovery." Alzheimers Dement 13(3): 236-246.

Ehrenberg, A. J., et al. (2018). "Neuropathologic Correlates of Psychiatric Symptoms in Alzheimer's Disease." J Alzheimers Dis 66(1): 115-126.

Ostlund, H., et al. (2003). "Estrogen receptor gene expression in relation to neuropsychiatric disorders." Ann N Y Acad Sci 1007: 54-63.

Chandler, D. J., et al. (2014). "Heterogeneous organization of the locus coeruleus projections to prefrontal and motor cortices." Proc Natl Acad Sci U S A 111(18): 6816-6821.

Oh, J., et al. (2019). "Profound degeneration of wake-promoting neurons in Alzheimer's disease." Alzheimers Dement 15(10): 1253-1263.

Van Egroo, M., et al. (2021). "Associations between locus coeruleus integrity and nocturnal awakenings in the context of Alzheimer's disease plasma biomarkers: a 7T MRI study." Alzheimers Res Ther 13(1): 159.

Heneka, M. T., et al. (2006). "Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice." J Neurosci 26(5): 1343-1354.

Kalinin, S., et al. (2007). "Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease." Neurobiol Aging 28(8): 1206-1214.

Heneka, M. T., et al. (2010). "Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine." Proc Natl Acad Sci U S A 107(13): 6058-6063.

Jardanhazi-Kurutz, D., et al. (2010). "Induced LC degeneration in APP/PS1 transgenic mice accelerates early cerebral amyloidosis and cognitive deficits." Neurochem Int 57(4): 375-382.

Chalermpalanupap, T., et al. (2013). "Targeting norepinephrine in mild cognitive impairment and Alzheimer's disease." Alzheimers Res Ther 5(2): 21.

Varma, V. R., et al. (2021). "Abnormal brain cholesterol homeostasis in Alzheimer's disease-a targeted metabolomic and transcriptomic study." NPJ Aging Mech Dis 7(1): 11.

Feringa, F. M. and R. van der Kant (2021). "Cholesterol and Alzheimer's Disease; From Risk Genes to Pathological Effects." Front Aging Neurosci 13: 690372.

Ehrenberg, A. J., et al. (2023). "Priorities for research on neuromodulatory subcortical systems in Alzheimer's disease: Position paper from the NSS PIA of ISTAART." Alzheimers Dement 19(5): 2182-2196.